nf-core/hicar

Pipeline for HiCAR data, a robust and sensitive multi-omic co-assay for simultaneous measurement of transcriptome, chromatin accessibility and cis-regulatory chromatin contacts.

NextflowPythonRGroovyOtherworkflowpipelinenextflowatac-seqtranscriptomehicmulti-omicsnf-coreatachicar
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Introduction nf-core/hicar is a bioinformatics best-practice analysis pipeline for HiC on Accessible Regulatory DNA (HiCAR) data, a robust and sensitive assay for simultaneous measurement of chromatin accessibility and cis-regulatory chromatin contacts. Unlike the immunoprecipitation-based methods such as HiChIP, PlAC-seq and ChIA-PET, HiCAR does not require antibodies. HiCAR utilizes a Transposase-Accessible Chromatin assay to anchor the chromatin interactions. HiCAR is a tool to study chromatin...
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