openpharma/mmrm

Mixed Models for Repeated Measures (MMRM) in R.

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This is stars and forks stats for /openpharma/mmrm repository. As of 10 May, 2024 this repository has 71 stars and 13 forks.

mmrm Mixed models for repeated measures (MMRM) are a popular choice for analyzing longitudinal continuous outcomes in randomized clinical trials and beyond; see Cnaan, Laird and Slasor (1997) for a tutorial and Mallinckrodt, Lane and Schnell (2008) for a review. This package implements MMRM based on the marginal linear model without random effects using Template Model Builder (TMB) which enables fast and robust model fitting. Users can specify a variety of covariance matrices, weight observations,...
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