gatelabNW/csf_aging

Single cell transcriptomics reveals cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment

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This is stars and forks stats for /gatelabNW/csf_aging repository. As of 25 Apr, 2024 this repository has 22 stars and 15 forks.

Single cell transcriptomics reveals cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment Gate Lab at Northwestern University Abstract Cerebrospinal fluid (CSF) contains a tightly regulated immune system. Yet, little is known about how CSF immunity is altered with aging or neurodegenerative disease. Here, we performed single cell RNA sequencing on CSF from 45 cognitively normal subjects ranging from 54-82 years old. We reveal upregulation of lipid transport...
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